Infectious bovine rhinotracheitis (IBR) is a respiratory disease of cattle caused by bovine herpesvirus type 1 (BoHV-1).
BoHV-1 positive herds experience significant economic losses due to poor production and export restrictions.
Several countries have already obtained an IBR free status, others are currently running IBR eradication programs.
IBR marker vaccines allow for the differentiation of animals vaccinated and those infected with a field virus strain.
The development of marker vaccines facilitated the establishment of control programs aiming at eradication of the disease.
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